Journal: Biosensors

Article Title: Insights into the Fabrication and Electrochemical Aspects of Paper Microfluidics-Based Biosensor Module

doi: 10.3390/bios13090891

Figure Lengend Snippet: Scientific survey conducted through the online database “PubMed” from 2007 to 2022 using the keywords “microfluidic paper-based analytical device” or “paper-based microfluidics.”.

Article Snippet: 6 , Lidocaine , SWV , Integrated graphene-based paper microfluidic electrode. Laser printing and NIR drying utilized for fabrication. , 6 , Filter paper (Whatman, φ = 55 mm with particle retention of 20–25 μm) , 1–100 μM , 0.8 μM , Serum and blood , [ ] .

Techniques:

Journal: Biosensors

Article Title: Insights into the Fabrication and Electrochemical Aspects of Paper Microfluidics-Based Biosensor Module

doi: 10.3390/bios13090891

Figure Lengend Snippet: ( I ) ( a ) Schematic representation of step−wise fabrication of a paper−based microfluidic device using photolithography and ( b ) Following photolithography, patterned paper was oxidized using oxygen plasma to make the surface more hydrophilic. Reprinted with permission from . ( II ) Steps involved in the fabrication of paper−based microfluidic devices using wax printing ( a ) depicts the design of the layout on the monitor, printing device, and wax reflow machine, ( b – d ) represents the design layout printed via wax printer on the paper. Reprinted with permission from . ( III ) Schematic representation of step−wise fabrication of paper−based microfluidic devices using inkjet printing. Reprinted with permission from . ( IV ) Representation of the fabrication of paper−based microfluidic devices using screen printing. Reprinted with permission from .

Article Snippet: 6 , Lidocaine , SWV , Integrated graphene-based paper microfluidic electrode. Laser printing and NIR drying utilized for fabrication. , 6 , Filter paper (Whatman, φ = 55 mm with particle retention of 20–25 μm) , 1–100 μM , 0.8 μM , Serum and blood , [ ] .

Techniques: Clinical Proteomics

Journal: Biosensors

Article Title: Insights into the Fabrication and Electrochemical Aspects of Paper Microfluidics-Based Biosensor Module

doi: 10.3390/bios13090891

Figure Lengend Snippet: ( I ) Illustration showing the paper microfluidic−based wearable sensor for cortisol sensing in sweat ( A ) depicts the SPE and paper−based microfluidic with its different zones, ( B ) depicts the paper−based microfluidic functionalized with antibodies and different reagents, ( C ) cortisol addition in the loading zone, ( D ) cortisol and cortisol−AChE flowing towards the reaction zone, ( E ) folding of the loading paper, ( F ) addition of buffer to start the enzymatic reaction (inset shows generation of the electroactive thiocholine via the enzymatic reaction), ( G ) calibration curve obtained via microfluidic device (inset shows the corresponding amperometric curves), ( H ) calibration curve obtained in sweat samples with and without spiking cortisol (inset shows the corresponding amperometric curves). ( II ) Schematic representing the cortisol tracking of an individual during cycling by a smartphone−based device. The steps include ( A ) sampling and ( B ) monitoring data via NFC on a smartphone. Reprinted with permission from . ( III ) Schematic representing the two designs constructed for paper–based analytical sensing: ( A ) design 1, which includes one short “T” piece for blending and two straight strips, ( B ) design 2, a straight strip for dilution and a long “T” −shaped sampler, ( C ) Schematic (above) and image (below) of the assembled device. ( IV ) A bar diagram representing the current intensities of glucose concentrations when directly deposited (blue bars) and 20−times diluted samples (green bars) on the electrochemical platform. ( V ) Illustration depicting the enzymatic reaction for sucrose hydrolysis by a paper microfluidics−based electrochemical system. Reprinted with permission from .

Article Snippet: 6 , Lidocaine , SWV , Integrated graphene-based paper microfluidic electrode. Laser printing and NIR drying utilized for fabrication. , 6 , Filter paper (Whatman, φ = 55 mm with particle retention of 20–25 μm) , 1–100 μM , 0.8 μM , Serum and blood , [ ] .

Techniques: Sampling, Construct, Stripping Membranes

Journal: Biosensors

Article Title: Insights into the Fabrication and Electrochemical Aspects of Paper Microfluidics-Based Biosensor Module

doi: 10.3390/bios13090891

Figure Lengend Snippet: ( I ) Schematic depicting the 3−D sequential paper microfluidic−based electrochemical platform for recognizing ascorbic acid. ( II ) Operation of the analytical device using a flow−through configuration ( A ) depicts the starting position and ( B ) depicts the position where reagent will be introduced. ( III ) The flow−through sePAD is depicted schematically with various channel diameters. ( IV ) Plot illustrating the amperograms of ascorbic acid in relation to channel width. Reprinted with permission from . ( V ) Pictorial representation showing the microfluidic flow cell configuration for detection of glucose ( a , b ), Image of the experimental equipment, including the potentiostat, collection vessel, carbon−coated−SPE electrode, and syringe pump ( c ). ( VI ) The position of the flow cell’s working, reference, and counter electrodes is depicted in the image. Reprinted with permission from .

Article Snippet: 6 , Lidocaine , SWV , Integrated graphene-based paper microfluidic electrode. Laser printing and NIR drying utilized for fabrication. , 6 , Filter paper (Whatman, φ = 55 mm with particle retention of 20–25 μm) , 1–100 μM , 0.8 μM , Serum and blood , [ ] .

Techniques:

Journal: Biosensors

Article Title: Insights into the Fabrication and Electrochemical Aspects of Paper Microfluidics-Based Biosensor Module

doi: 10.3390/bios13090891

Figure Lengend Snippet: Paper microfluidics-based electrochemical devices for the detection of small molecules.

Article Snippet: 6 , Lidocaine , SWV , Integrated graphene-based paper microfluidic electrode. Laser printing and NIR drying utilized for fabrication. , 6 , Filter paper (Whatman, φ = 55 mm with particle retention of 20–25 μm) , 1–100 μM , 0.8 μM , Serum and blood , [ ] .

Techniques: Modification, Pore Size, Membrane, Chromatography, Labeling

Journal: Biosensors

Article Title: Insights into the Fabrication and Electrochemical Aspects of Paper Microfluidics-Based Biosensor Module

doi: 10.3390/bios13090891

Figure Lengend Snippet: ( I ) Schematic showing the aptasensor–based paper microfluidic device for the detection of NSE and CEA antigens. ( II ) Plot showing the DPV readout for electrochemical sensing of CEA. ( III ) DPV responses to various NSE antigen doses. Reprinted with permission from . ( IV ) Pictorial representation showing the stepwise designing of a paper–microfluidics–based platform for analytical sensing of IFN-γ ( A ) and origami folding ( B ), ( V ) Step-by-step fabrication of human IFN-γ immunosensor. Reprinted with permission from .

Article Snippet: 6 , Lidocaine , SWV , Integrated graphene-based paper microfluidic electrode. Laser printing and NIR drying utilized for fabrication. , 6 , Filter paper (Whatman, φ = 55 mm with particle retention of 20–25 μm) , 1–100 μM , 0.8 μM , Serum and blood , [ ] .

Techniques: